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Comparative Studies on the Catalytic Roles of Cytochrome P450 2C9 and Its Cys- and Leu-Variants in the Oxidation of Warfarin, Flurbiprofen, and Diclofenac by Human Liver Microsomes

BiochemistryMedicineCytochrome P450 2C9Catalytic RolesMetabolomic ProfilingHepatotoxicityMetabolomicsPharmacologyHuman MetabolismDrug-induced Liver InjuryToxicological MechanismComparative StudiesToxicogenomics