Programmed cell death (apoptosis) as a possible pathway to metalloproteinase activation and fetal membrane degradation in premature rupture of membranes

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

Zoltán N. Oltval, Curt Milliman, Stanley J. Korsmeyer · Cell · 1993 · 6K citations

Life Sciences, Cell Biology, Molecular Biology +12

Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo.

Toshiyuki Miyashita, Stanisław Krajewski, Maryla Krajewska et al. · PubMed · 1994 · 2.2K citations

Life Sciences, Cell Biology, Oncology +13

Definition of a consensus binding site for p53

Wafik S. El‐Deiry, Scott E. Kern, Jennifer A. Pietenpol et al. · Nature Genetics · 1992 · 2K citations

Life Sciences, Molecular Biology, Molecular Genetics +10

The TIMP2 Membrane Type 1 Metalloproteinase “Receptor” Regulates the Concentration and Efficient Activation of Progelatinase A

Georgina S. Butler, Michael J. Butler, Susan J. Atkinson et al. · Journal of Biological Chemistry · 1998 · 570 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Sequence-specific transcriptional activation is essential for growth suppression by p53.

Jennifer A. Pietenpol, Takashi Tokino, Sam Thiagalingam et al. · Proceedings of the National Academy of Sciences · 1994 · 408 citations

Medicine, Molecular Biology, Oncology +13