Concepedia

Rapid Synthesis of the A−E Fragment of Ciguatoxin CTX3C

J. Stephen Clark, Joanne M. Conroy, Alexander J. Blake

Organic Letters · 2007 · 37 citations · 15 references

DOI

Concepts

Abstract

The A-E fragment of the marine natural product CTX3C has been prepared in an efficient manner by using a strategy in which two-directional and iterative ring-closing metathesis (RCM) reactions were employed for ring construction.

References

15

Synthesis and Activity of a New Generation of Ruthenium-Based Olefin Metathesis Catalysts Coordinated with 1,3-Dimesityl-4,5-dihydroimidazol-2-ylidene Ligands

Matthias Scholl, Sheng Ding, Choon Woo Lee et al. · Organic Letters · 1999 · 3.4K citations

, , +15

A Series of Well‐Defined Metathesis Catalysts–Synthesis of [RuCl<sub>2</sub>(CHR′)(PR<sub>3</sub>)<sub>2</sub>] and Its Reactions

Peter Schwab, Marcia B. France, Joseph W. Ziller et al. · Angewandte Chemie International Edition in English · 1995 · 1.5K citations

, , +16

Engineering Crystal Symmetry and Polar Order in Molecular Host Frameworks

K.T. Holman, A.M. Pivovar, Michael D. Ward · Science · 2001 · 337 citations

, , +17

Ciguatoxin: Isolation and Chemical Nature

Paul J. Scheuer, Wataru Takahashi, Junzo Tsutsumi et al. · Science · 1967 · 284 citations

, , +11

Total Synthesis of Ciguatoxin CTX3C

Masahiro Hirama, Tohru Oishi, Hisatoshi Uehara et al. · Science · 2001 · 233 citations

, , +13