PPAR-γ2 and PTPRD gene polymorphisms influence type 2 diabetes patients' response to pioglitazone in China

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

Jürgen M. Lehmann, Linda B. Moore, Tracey Smith-Oliver et al. · Journal of Biological Chemistry · 1995 · 3.6K citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

Isabelle Issemann, Stephen Green · Nature · 1990 · 3.5K citations

Life Sciences, Biochemistry, Endocrinology +12

A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

Samir S. Deeb, Lluís Fajas, Masami Nemoto et al. · Nature Genetics · 1998 · 1.3K citations · Full text

Medicine, Endocrinology, Pharmacology +17

Effect of Pioglitazone on Abdominal Fat Distribution and Insulin Sensitivity in Type 2 Diabetic Patients

Yoshinori Miyazaki, Archana Mahankali, Masafumi Matsuda et al. · The Journal of Clinical Endocrinology & Metabolism · 2002 · 699 citations

Medicine, Endocrinology, Pharmacology +17

Pioglitazone hydrochloride monotherapy improves glycemic control in the treatment of patients with type 2 diabetes: a 6-month randomized placebo-controlled dose-response study. The Pioglitazone 001 Study Group.

S Aronoff, Sidney Rosenblatt, Susan S. Braithwaite et al. · Diabetes Care · 2000 · 629 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17