Concepedia

Transforming terpene feedstock into polyketide architecture

Philipp Winter, Carine Vaxelaire, Christoph Heinz, Mathias Christmann

Chemical Communications · 2010 · 24 citations · 31 references

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Abstract

The Cu-catalyzed synthesis of skipped 1,4-dienes from allylic acetates and vinyl-Grignard reagents is key to bidirectional modifications of acyclic terpene acetates. As a result, trisubstituted double bond containing subunits can be readily transferred into complex polyketides from inexpensive bulk terpenes.

References

31

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