Concepedia

Highly Enantioselective Conjugate Addition of Nitromethane to Chalcones Using Bifunctional Cinchona Organocatalysts

Benedek Vakulya, Szilárd Varga, Tibor Soós

Organic Letters · 2005 · 979 citations · 10 references

DOI

Concepts

Abstract

Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields.

References

10

Encoding and decoding hydrogen-bond patterns of organic compounds

Margaret C. Etter · Accounts of Chemical Research · 1990 · 4.6K citations

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In the Golden Age of Organocatalysis

Peter I. Dalko, Lionel Moisan · Angewandte Chemie International Edition · 2004 · 2.6K citations

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Asymmetric Organic Catalysis with Modified Cinchona Alkaloids

Shi‐Kai Tian, Yonggang Chen, Jianfeng Hang et al. · Accounts of Chemical Research · 2004 · 618 citations

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Addition of aromatic thiols to conjugated cycloalkenones, catalyzed by chiral .beta.-hydroxy amines. A mechanistic study of homogeneous catalytic asymmetric synthesis

Henk Hiemstra, Hans Wynberg · Journal of the American Chemical Society · 1981 · 442 citations

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Highly Efficient Dynamic Kinetic Resolution of Azlactones by Urea‐Based Bifunctional Organocatalysts

Albrecht Berkessel, Felix Cleemann, Santanu Mukherjee et al. · Angewandte Chemie International Edition · 2005 · 266 citations

, , +11