Concepedia

Determination of the inhibitory potential of 6 fluoroquinolones on CYP1A2 and CYP2C9 in human liver microsomes

Li Zhang, Minji Wei, Caiyun Zhao, Huimin Qi

Acta Pharmacologica Sinica · 2008 · 39 citations · 26 references

Concepts

MedicinePharmacokineticsPharmacologyHepatic PharmacokineticsCytochrome P450 EnzymesCytochrome P450 InteractionsCytochrome P450-mediated MetabolismHepatic Drug MetabolismHepatotoxicity MechanismsPharmacokinetics In Liver DiseaseCyp1a2 Drug MetabolismCytochrome P450 2C9Cytochrome P450 Enzyme ActivityCytochrome P450 Human Liver MicrosomesHepatic Drug Interactions

References

26

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

Mark A. Bradford · Analytical Biochemistry · 1976 · 225.4K citations

Life Sciences, Biochemistry, Protein Biochemistry +7

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Marion M. Bradford · Analytical Biochemistry · 1976 · 211.2K citations

Life Sciences, Biochemistry, Protein Biochemistry +7

VALIDATED ASSAYS FOR HUMAN CYTOCHROME P450 ACTIVITIES

Robert L. Walsky, R. Scott Obach · Drug Metabolism and Disposition · 2004 · 504 citations

Medicine, Pharmacokinetics, Pharmacology +15

Evaluation of Cytochrome P450 Probe Substrates Commonly Used by the Pharmaceutical Industry to Study in Vitro Drug Interactions

Rae Yuan, Soraya Madani, Xiaoxiong Wei et al. · Drug Metabolism and Disposition · 2002 · 324 citations

Medicine, Pharmacokinetics, Pharmacology +16

Effect of common organic solvents on in vitro cytochrome P450-mediated metabolic activities in human liver microsomes.

Nathalie Chauret, Annick Gauthier, Deborah A. Nicoll‐Griffith · PubMed · 1998 · 310 citations

Medicine, Biochemistry, Pharmacology +16