Multi-Locus Sequence Typing of Enteroaggregative Escherichia coli Isolates from Nigerian Children Uncovers Multiple Lineages

Iruka N. Okeke, Faith Wallace-Gadsden, Hannah R. Simons, Nicholas Matthews, Amy S. Labar, Jennifer Hwang, John Wain

PLoS ONE · 2010 · 97 citations · 71 references

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Abstract

We have developed a molecular phylogenetic framework, which demonstrates that although grouped by a shared phenotype, the category of 'EAEC' encompasses multiple pathogenic lineages. Principal among isolates from Nigeria were ST10-complex EAEC that were associated with diarrhea in children over one year and ECOR D strains that share horizontally acquired loci.

References

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