K-ras andp53 mutations in stage I gallbladder carcinoma with an anomalous junction of the pancreaticobiliary duct

Abstract

These results suggest that K-ras mutation may be important in the early stage of carcinogenesis of the gallbladder mucosa with AJPBD, and that p53 mutations may also contribute to the early stage of carcinogenesis of the gallbladder mucosa, regardless of AJPBD: