Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Michael C. Wei, Wei‐Xing Zong, Emily H. Cheng, +7

Science

Identification and characterization of a new member of the TNF family that induces apoptosis

Steven R. Wiley, Ken Schooley, Pamela J. Smolak, +8

Immunity

InflammationCytokineSignaling PathwayMedicineReceptor Tyrosine Kinase +10

Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo

Henning Walczak, Robert E. Miller, K. Ariail, +13

Nature Medicine

InflammationAnti-inflammatoryMedicineApoptosisPharmacology +7

Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

Peter Carmeliet, Yuval Dor, Jean-Marc Herbert, +13

Nature

Tumor BiologyHypoxia-mediated ApoptosisRedox RegulatorApoptosisHypoxia (Medicine) +13

Safety and antitumor activity of recombinant soluble Apo2 ligand

Avi Ashkenazi, Roger Pai, Sharon Fong, +15

Journal of Clinical Investigation

Apo2l MrnaMedicinal ChemistryApo2l TreatmentAntitumor ActivityMedicine +11

X-linked IAP is a direct inhibitor of cell-death proteases

Quinn L. Deveraux, Ryōsuke Takahashi, Guy S. Salvesen, +1

Nature

Protein FunctionApoptosisAutophagyX-linked IapCell Death +3

Movement of Bax from the Cytosol to Mitochondria during Apoptosis

Keith G. Wolter, Yi‐Te Hsu, Carolyn L. Smith, +3

The Journal of Cell Biology

Induction of Apoptosis by Apo-2 Ligand, a New Member of the Tumor Necrosis Factor Cytokine Family

Robert Pitti, Scot A. Marsters, Siegfried Ruppert, +3

Journal of Biological Chemistry

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

Quinn L. Deveraux

The EMBO Journal

Signal TransductionApoptosisImmunologyCell DeathCytochrome C +7

Regulated Targeting of BAX to Mitochondria

Ing Swie Goping, Atan Gross, Josée N. Lavoie, +5

The Journal of Cell Biology

ApoptosisImmunologyMolecular BiologyCell DeathCytoskeleton +14