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Synthesis and structure–activity relationships of 1,2,3,4-tetrahydropyrido[2,3-b]pyrazines as potent and selective inhibitors of the anaplastic lymphoma kinase

Pharmaceutical ChemistryMedicineSelective InhibitorsAnti-cancer AgentStructure–activity RelationshipsPharmacologyAnaplastic Lymphoma KinaseBiomolecular EngineeringDrug Discovery