Thelma S. Angeles

Motoneuron Apoptosis Is Blocked by CEP-1347 (KT 7515), a Novel Inhibitor of the JNK Signaling Pathway

Anna C. Maroney, Marcie A. Glicksman, Alie N. Basma et al. · Journal of Neuroscience · 1998 · 292 citations · Full text

Lestaurtinib (CEP701) is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders

Elizabeth O. Hexner, Cynthia Serdikoff, Mahfuza Jan et al. · Blood · 2007 · 251 citations · Full text

CEP-1347 (KT7515), a Semisynthetic Inhibitor of the Mixed Lineage Kinase Family

Anna C. Maroney, James P. Finn, Thomas J. Connors et al. · Journal of Biological Chemistry · 2001 · 204 citations · Full text

Sustained in vivo regression of Dunning H rat prostate cancers treated with combinations of androgen ablation and Trk tyrosine kinase inhibitors, CEP-751 (KT-6587) or CEP-701 (KT-5555).

Daniel J. George, Craig A. Dionne, Jacques Jani et al. · PubMed · 1999 · 126 citations

Urology, Androgen Ablation, Chemoprevention Strategy +14

CEP-7055: a novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models.

Bruce Ruggeri, J. B. Singh, Diane E. Gingrich et al. · PubMed · 2003 · 124 citations

Chemoprevention Strategy, Antitumor Efficacy, Tumor Biology +19