Infectivity Enhancement by HIV-1 Nef Is Dependent on the Pathway of Virus Entry: Implications for HIV-Based Gene Transfer Systems

In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector

Luigi Naldini, Ulrike Blömer, Philippe Gallay et al. · Science · 1996 · 4.9K citations

Immunology, Retroviral Vector System, Gene Delivery +17

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

Angus Dalgleish, Peter C. L. Beverley, Paul R. Clapham et al. · Nature · 1984 · 3.5K citations · Full text

Human Retrovirus, Immunology, Antiviral Response +8

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

David Klatzmann, Éric Champagne, S. Chamaret et al. · Nature · 1984 · 2.4K citations

Viral Persistence, Human Retrovirus, Immunology +9

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

Paul J. Maddon, Angus Dalgleish, J. Steven McDougal et al. · Cell · 1986 · 2K citations

Adaptive Immune System, Neurovirology, Medicine +12

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

Harry W. Kestier, D J Ringler, Kazuyasu Mori et al. · Cell · 1991 · 1.6K citations

Viral Replication, Molecular Virology, Medicine +11