Stabilizing parallel G-quadruplex DNA by a new class of ligands: Two non-planar alkaloids through interaction in lateral grooves

Prevalence of quadruplexes in the human genome

J Huppert, Shankar Balasubramanian · Nucleic Acids Research · 2005 · 1.7K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +16

Telomestatin, a Potent Telomerase Inhibitor That Interacts Quite Specifically with the Human Telomeric Intramolecular G-Quadruplex

Mu-Yong Kim, Hariprasad Vankayalapati, Kazuo Shin‐ya et al. · Journal of the American Chemical Society · 2002 · 515 citations

Life Sciences, Biochemistry, Molecular Biology +17

Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors

Martin L. Read, R. John Harrison, Bárbara Romagnoli et al. · Proceedings of the National Academy of Sciences · 2001 · 484 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

The High-Resolution Crystal Structure of a Parallel-Stranded Guanine Tetraplex

Gerard Laughlan, Alastair I.H. Murchie, D. Norman et al. · Science · 1994 · 482 citations

Life Sciences, Biochemistry, Molecular Biology +12

Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands

Jean‐François Riou, Lionel Guittat, Patrick Mailliet et al. · Proceedings of the National Academy of Sciences · 2002 · 392 citations

Life Sciences, Molecular Biology, Oncology +17