Polymerase chain reaction heteroduplex polymorphism analysis by entangled solution capillary electrophoresis

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

Masato Orita, Youichi Suzuki, Takao Sekiya et al. · Genomics · 1989 · 3.5K citations

Life Sciences, Genetics, Molecular Genetics +16

Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes.

Val C. Sheffield, David R. Cox, Leonard S. Lerman et al. · Proceedings of the National Academy of Sciences · 1989 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Reactivity of cytosine and thymine in single-base-pair mismatches with hydroxylamine and osmium tetroxide and its application to the study of mutations.

Richard G.H. Cotton, Nanda R. Rodrigues, R. Duncan Campbell · Proceedings of the National Academy of Sciences · 1988 · 625 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Detection of Single Base Substitutions by Ribonuclease Cleavage at Mismatches in RNA:DNA Duplexes

R Myers, Zoia Larin, Tom Maniatis · Science · 1985 · 532 citations

Life Sciences, Genetics, Molecular Biology +14

Detecting single base substitutions as heteroduplex polymorphisms

Marga Belle White, Magda Carvalho, David Derse et al. · Genomics · 1992 · 359 citations

Life Sciences, Genetics, Molecular Genetics +6