Minocycline Slows Disease Progression in a Mouse Model of Amyotrophic Lateral Sclerosis

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D.R. Rosen, Teepu Siddique, David T. Patterson et al. · Nature · 1993 · 7K citations

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Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation

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Gentry N. Patrick, Lawrence Zukerberg, Margareta Nikolić et al. · Nature · 1999 · 1.5K citations

Neurodegenerative Diseases, Neuroregeneration, Signal Transduction +12

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

Philip C. Wong, Carlos A. Pardo, David Borchelt et al. · Neuron · 1995 · 1.4K citations

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

Lucie Bruijn, Megan K. Houseweart, Shinsuke Kato et al. · Science · 1998 · 1.2K citations