Inhibition of lipopolysaccharide-inducible nitric oxide synthase expression by acteoside through blocking of AP-1 activation

Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide.

Q W Xie, R Whisnant, C F Nathan · The Journal of Experimental Medicine · 1993 · 1.1K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide.

Charles J. Lowenstein, Evan Alley, Pravin Raval et al. · Proceedings of the National Academy of Sciences · 1993 · 1.1K citations

Life Sciences, Immunology, Molecular Biology +17

Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase.

Csaba Szabó, Garry J. Southan, Christoph Thiemermann · Proceedings of the National Academy of Sciences · 1994 · 409 citations · Full text

Veterinary Medicine, Pathobiology, Pharmacology +11

Inhibition of lipopolysaccharide‐inducible nitric oxide synthase, TNF‐<i>α</i> and COX‐2 expression by sauchinone effects on I‐<i>κ</i>B<i>α</i> phosphorylation, C/EBP and AP‐1 activation

Ae Kyung Lee, Sang Hyun Sung, Young Choong Kim et al. · British Journal of Pharmacology · 2003 · 276 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13

Pyrrolidine Dithiocarbamate Inhibits Induction of Nitric Oxide Synthase Activity in Rat Alveolar Macrophages

Michael P. Sherman, Ernesto E. Aeberhard, Vivian Wong et al. · Biochemical and Biophysical Research Communications · 1993 · 250 citations

Medicine, Pharmacology, Inflammation +9