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Publication | Open Access

Insulin Degradation by Acinar Cell Proteases Creates a Dysfunctional Environment for Human Islets Before/After Transplantation: Benefits of α-1 Antitrypsin Treatment

DOIFull Paper Access

39

Citations

37

References

2011

Year

Gopalakrishnan Loganathan, Rajinder Dawra, Subbiah Pugazhenthi, Zhiguang Guo, Sajjad Soltani, Alexander C. Wiseman, Mark A Sanders, Klearchos K. Papas, Kumaravel Velayutham, Ashok K. Saluja,
Transplantation

Abstract

Culture of impure human islet fractions in the presence of A1AT prevents insulin degradation and improves islet recovery.

References

YearCitations

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