Simultaneous analysis of docetaxel and the formulation vehicle polysorbate 80 in human plasma by liquid chromatography/tandem mass spectrometry

Explaining Interindividual Variability of Docetaxel Pharmacokinetics and Pharmacodynamics in Asians Through Phenotyping and Genotyping Strategies

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Role of human cytochrome P450 3A4 and 3A5 in the metabolism of taxotere and its derivatives: enzyme specificity, interindividual distribution and metabolic contribution in human liver

Magang Shou, Michel Martinet, Kenneth R. Korzekwa et al. · Pharmacogenetics · 1998 · 190 citations

Medicine, Biochemistry, Pharmacology +17

Low systemic exposure of oral docetaxel in mice resulting from extensive first-pass metabolism is boosted by ritonavir.

Heleen A. Bardelmeijer, Mariët Ouwehand, Tessa Buckle et al. · PubMed · 2002 · 135 citations

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Sensitive liquid chromatography–mass spectrometry assay for quantitation of docetaxel and paclitaxel in human plasma

Robert A. Parise, Ramesh K. Ramanathan, William C. Zamboni et al. · Journal of Chromatography B · 2002 · 128 citations

Pharmacy, Pharmacokinetics, Pharmacology +11

Rapid esterase-sensitive breakdown of polysorbate 80 and its impact on the plasma pharmacokinetics of docetaxel and metabolites in mice.

Olaf van Tellingen, Jos H. Beijnen, Jaap Verweij et al. · PubMed · 1999 · 114 citations

Pharmacy, Pharmacokinetics, Pharmacology +11