A missense mutation in the glucagon receptor gene is associated with non–insulin–dependent diabetes mellitus

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

Steffan N. Ho, Henry D. Hunt, Robert M. Horton et al. · Gene · 1989 · 7.5K citations

Life Sciences, Biotechnology, Molecular Biology +10

Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).

Richard S. Spielman, Ralph McGinnis, Warren J. Ewens · PubMed · 1993 · 3.7K citations

Life Sciences, Genetics, Molecular Genetics +15

Mutation in mitochondrial tRNALeu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness

J. M. W. van den Ouweland, H.H.P.J. Lemkes, W. Ruitenbeek et al. · Nature Genetics · 1992 · 1.1K citations

Life Sciences, Genetics, Molecular Genetics +15

Studies of pancreatic alpha cell function in normal and diabetic subjects

Roger H. Unger, E Aguilar-Parada, Walter A. Müller et al. · Journal of Clinical Investigation · 1970 · 837 citations · Full text

Medicine, Endocrinology, Internal Medicine +10

Familial Hyperglycemia Due to Mutations in Glucokinase -- Definition of a Subtype of Diabetes Mellitus

Philippe Froguel, Habib Zouali, Nathalie Vionnet et al. · New England Journal of Medicine · 1993 · 741 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13