Concepedia

Antiviral Amentoflavone from Selaginella sinensis

Shuang‐Cheng Ma, Paul Pui‐Hay But, V.Eng-Choon Ooi, Yuehua He, Spencer Hon‐Sun Lee, Song-Fong LEE, Rui‐Chao Lin

Biological and Pharmaceutical Bulletin · 2001 · 146 citations · 9 references

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Abstract

Amentoflavone and three other flavonoids were isolated from the ethanol extract of Selaginella sinensis. Amentoflavone showed potent antiviral activity against respiratory syncytial virus (RSV), with an IC50 of 5.5 microg/ml. The contents of amentoflavone in nine species of Selaginella were determined by reversed-phase HPLC. S. sinensis showed a higher content of 1.13%.

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