Concepedia

mGluR5: Exploration of Orthosteric and Allosteric Ligand Binding Pockets and Their Applications to Drug Discovery

Christina Mølck, Kasper Harpsøe, David E. Gloriam, Jesper Mosolff Mathiesen, Søren Nielsen, Hans Bräuner‐Osborne

Neurochemical Research · 2014 · 31 citations · 62 references

DOI

Concepts

References

62

High-Resolution Crystal Structure of an Engineered Human β <sub>2</sub> -Adrenergic G Protein–Coupled Receptor

Vadim Cherezov, Daniel M. Rosenbaum, Michael A. Hanson et al. · Science · 2007 · 3.3K citations · Full text

, , +17

The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints

Robert Fredriksson, Malin C. Lagerström, Lars‐Gustav Lundin et al. · Molecular Pharmacology · 2003 · 2.9K citations

, , +13

Crystal structure of the human β2 adrenergic G-protein-coupled receptor

Søren G. F. Rasmussen, Hee‐Jung Choi, Daniel M. Rosenbaum et al. · Nature · 2007 · 1.9K citations

, , +16

Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists

Beili Wu, Ellen Y. T. Chien, Clifford D. Mol et al. · Science · 2010 · 1.8K citations

, , +17

The 2.6 Angstrom Crystal Structure of a Human A <sub>2A</sub> Adenosine Receptor Bound to an Antagonist

Veli‐Pekka Jaakola, Mark T. Griffith, Michael A. Hanson et al. · Science · 2008 · 1.8K citations · Full text

, , +17