Development of a bispecific monoclonal antibody for use in molecular hybridisation

Detection of specific sequences among DNA fragments separated by gel electrophoresis

E.M. Southern · Journal of Molecular Biology · 1975 · 32.8K citations

Life Sciences, Molecular Biology, Molecular Genetics +12

Continuous cultures of fused cells secreting antibody of predefined specificity

Georges Köhler, César Milstein · Nature · 1975 · 17.2K citations

Pharmacy, Cell Biology, Immunology +11

THE UNLABELED ANTIBODY ENZYME METHOD OF IMMUNOHISTOCHEMISTRY PREPARATION AND PROPERTIES OF SOLUBLE ANTIGEN-ANTIBODY COMPLEX (HORSERADISH PEROXIDASE-ANTIHORSERADISH PEROXIDASE) AND ITS USE IN IDENTIFICATION OF SPIROCHETES

Ludwig A. Sternberger, Paul H. Hardy, John J. Cuculis et al. · Journal of Histochemistry & Cytochemistry · 1970 · 5.1K citations · Full text

Life Sciences, Biochemistry, Immunology +16

Derivation of specific antibody‐producing tissue culture and tumor lines by cell fusion

Georges Köhler, César Milstein · European Journal of Immunology · 1976 · 1.9K citations

Life Sciences, Immunology, Oncology +12

Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay

Bertrand Friguet, Alain Chaffotte, Lisa Djavadi‐Ohaniance et al. · Journal of Immunological Methods · 1985 · 1.2K citations

Life Sciences, Biochemistry, Immunology +15