Effects of novel synthetic serine protease inhibitors on postoperative blood loss, coagulation parameters, and vascular relaxation after cardiac surgery

EFFECT OF APROTININ ON NEED FOR BLOOD TRANSFUSION AFTER REPEAT OPEN-HEART SURGERY

David Royston, Kenneth M. Taylor, Benjamin P. Bidstrup et al. · The Lancet · 1987 · 691 citations

Medicine, Perioperative Medicine, Surgery +10

Reexploration for Hemorrhage Following Coronary Artery Bypass Grafting<subtitle>Incidence and Risk Factors</subtitle>

Lawrence J. Dacey · Archives of Surgery · 1998 · 265 citations

Medicine, Cardiology, Surgery +12

Analyses of coronary graft patency after aprotinin use: Results from the international multicenter aprotinin graft patency experience (IMAGE) trial

Edwin L. Alderman, Jerrold H. Levy, Jeffrey Rich et al. · Journal of Thoracic and Cardiovascular Surgery · 1998 · 251 citations · Full text

Medicine, Cardiology, Surgery +11

Effects of high-dose aprotinin on blood loss, platelet function, fibrinolysis, complement, and renal function after cardiopulmonary bypass

B. Blauhut, Stan Necek, Jan Eva Doran et al. · Journal of Thoracic and Cardiovascular Surgery · 1991 · 249 citations

Medicine, Perioperative Medicine, Pharmacology +13

Aprotinin significantly decreases bleeding and transfusion requirements in patients receiving aspirin and undergoing cardiac operations

John M. Murkin, JoAnn Lux, N. A. Shannon et al. · Journal of Thoracic and Cardiovascular Surgery · 1994 · 154 citations · Full text

Medicine, Hematology, Perioperative Medicine +14