Andreas van de Locht

The ornithodorin-thrombin crystal structure, a key to the TAP enigma?

Andreas van de Locht, Milton T. Stubbs, Wolfram Bode et al. · The EMBO Journal · 1996 · 188 citations · Full text

Crystal Structure, Biophysics, Protein Folding +5

Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin.

Andreas van de Locht, Doriano Lamba, Margit Bauer et al. · The EMBO Journal · 1995 · 177 citations · Full text

Crystal Structure, Biochemistry, Medicine +4

The thrombin E192Q-BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin

Andreas van de Locht · The EMBO Journal · 1997 · 89 citations · Full text

Thrombopoiesis, Thrombosis, Signal Transduction +10

CU-2010—A Novel Small Molecule Protease Inhibitor with Antifibrinolytic and Anticoagulant Properties

Wulf Dietrich, Silke Nicklisch, Andreas Koster et al. · Anesthesiology · 2008 · 42 citations

Time‐domain <i>in vivo</i> near infrared fluorescence imaging for evaluation of matriptase as a potential target for the development of novel, inhibitor‐based tumor therapies

Joanna Napp, Christian Dullin, Friedemann Müller et al. · International Journal of Cancer · 2010 · 25 citations

Engineering, Oncologic Imaging, Inhibitor‐based Tumor Therapies +20