RETRACTED ARTICLE: HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

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Genetics, Molecular Biology, Hif-1 Subunits +21

Genes that mediate breast cancer metastasis to lung

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Breast Cancer Metastasis, Medicine, Breast Cancer +5

Lysyl oxidase is essential for hypoxia-induced metastasis

Janine T. Erler, Kevin L. Bennewith, Monica Nicolau et al. · Nature · 2006 · 1.3K citations

Biochemistry, Hypoxia (Medicine), Reactive Oxygen Specie +5

Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche

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Premetastatic Niche, Critical Mediator, Physiology +11

HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells

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Redox Signaling, Biochemistry, Redox Regulator +13