Concepedia

Chinese medicine Tongxinluo modulates vascular endothelial function by inducing eNOS expression via the PI-3K/Akt/HIF-dependent signaling pathway

Jun Qing Liang, Kun Wu, Zhen Jia, Chang Liu, Jin Ding, Shan Huang, Pei Yin, Xiang Wu, Cong Wei, Yi Wu,

Journal of Ethnopharmacology · 2010 · 43 citations · 28 references

DOI

Concepts

References

28

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

Stefanie Dimmeler, Ingrid Fleming, Beate Fißlthaler et al. · Nature · 1999 · 3.6K citations

, , +15

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

David Fulton, Jean‐Philippe Gratton, Timothy J. McCabe et al. · Nature · 1999 · 2.6K citations

, , +10

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals.

Yasuko Kureishi, Zhengyu Luo, Ichiro Shiojima et al. · Nature Medicine · 2000 · 1.4K citations

, , +12

Dimerization, DNA Binding, and Transactivation Properties of Hypoxia-inducible Factor 1

Bing‐Hua Jiang, Elizabeth Rue, Guang L. Wang et al. · Journal of Biological Chemistry · 1996 · 1.1K citations · Full text

, , +12

Regulation of the Erythropoietin Gene: Evidence That the Oxygen Sensor Is a Heme Protein

Mark A. Goldberg, Susan P. Dunning, H. Franklin Bunn · Science · 1988 · 1K citations

, , +14