STAT1-caspase 3 pathway in the apoptotic process associated with steroid-induced necrosis of the femoral head

Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone.

Robert S. Weinstein, R L Jilka, A. M. Parfitt et al. · Journal of Clinical Investigation · 1998 · 1.8K citations · Full text

Medicine, Endocrinology, Aging +16

Idiopathic bone necrosis of the femoral head. Early diagnosis and treatment

R. Paul Ficat · Journal of Bone and Joint Surgery - British Volume · 1985 · 1.3K citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +12

Pathogenesis and natural history of osteonecrosis

Yehudith Assouline-Dayan, Christopher Chang, Adam Greenspan et al. · Seminars in Arthritis and Rheumatism · 2002 · 786 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +11

Defective TNF-α-Induced Apoptosis in STAT1-Null Cells Due to Low Constitutive Levels of Caspases

Aseem Kumar, Mairead Commane, T W Flickinger et al. · Science · 1997 · 516 citations

Life Sciences, Cell Biology, Molecular Biology +16

Apoptosis of Osteocytes in Glucocorticoid-Induced Osteonecrosis of the Hip¹

Robert S. Weinstein, Richard W. Nicholas, Stavros C. Manolagas · The Journal of Clinical Endocrinology & Metabolism · 2000 · 378 citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +15