A mixed model reduces spurious genetic associations produced by population stratification in genome-wide association studies

PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses

Shaun Purcell, Benjamin M. Neale, Katherine EO Todd-Brown et al. · The American Journal of Human Genetics · 2007 · 36.1K citations · Full text

Life Sciences, Bioinformatics, Genetics +13

Principal components analysis corrects for stratification in genome-wide association studies

Alkes L. Price, Nick J. Patterson, Robert M. Plenge et al. · Nature Genetics · 2006 · 10.7K citations

Public Health, Biostatistics, Genetics +12

GCTA: A Tool for Genome-wide Complex Trait Analysis

Jian Yang, Sang Lee, Michael E. Goddard et al. · The American Journal of Human Genetics · 2010 · 9.3K citations · Full text

Life Sciences, Bioinformatics, Genetics +11

An integrated map of genetic variation from 1,092 human genomes

Nature · 2012 · 8.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

A unified mixed-model method for association mapping that accounts for multiple levels of relatedness

Jianming Yu, Gaël Pressoir, William H. Briggs et al. · Nature Genetics · 2005 · 4.3K citations

Life Sciences, Biostatistics, Genetics +12