Autoprocessing of the Vibrio cholerae RTX toxin by the cysteine protease domain

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.9K citations · Full text

Life Sciences, Bioinformatics, Sequence Analysis +14

PHYLIP-Phylogeny inference package (Version 3.2)

Joe Felsenstein · Cladistics · 1989 · 17.9K citations

Life Sciences, Bioinformatics, Evolutionary Biology +9

Fitting a mixture model by expectation maximization to discover motifs in biopolymers.

Trisha L. Bailey, Charles Elkan · PubMed · 1994 · 5.1K citations

Life Sciences, Bioinformatics, Computational Biology +16

Combining evidence using p-values: application to sequence homology searches.

Trisha L. Bailey, Michael Gribskov · Bioinformatics · 1998 · 1.3K citations · Full text

Life Sciences, Bioinformatics, Biostatistics +15

MEROPS: the peptidase database

Neil D. Rawlings · Nucleic Acids Research · 1999 · 803 citations · Full text

Life Sciences, Biochemistry, Bioinformatics +15