G20210A is a functional mutation in the prothrombin gene; effect on protein levels and 3′‐end formation

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis

SR Poort, FR Rosendaal, PH Reitsma et al. · Blood · 1996 · 3.1K citations · Full text

Medicine, Genetics, Molecular Genetics +15

ON ESTIMATING THE RELATION BETWEEN BLOOD GROUP AND DISEASE

Barnet Woolf · Annals of Human Genetics · 1955 · 2.7K citations

Public Health, Biostatistics, Hematology +7

Geographic Distribution of the 20210 G to A Prothrombin Variant

Carine J.M. Doggen, Ariella Zivelin, Valder R. Arruda et al. · Thrombosis and Haemostasis · 1998 · 702 citations · Full text

Medicine, Genetics, Molecular Genetics +17

Point mutations in AAUAAA and the poly (A) addition site: effects on the accuracy and efficiency of cleavage and polyadenylation<i>in vitro</i>

Michael Sheets, Stephen C. Ogg, Marvin Wickens · Nucleic Acids Research · 1990 · 502 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Combined effect of factor V Leiden and prothrombin 20210A on the risk of venous thromboembolism--pooled analysis of 8 case-control studies including 2310 cases and 3204 controls. Study Group for Pooled-Analysis in Venous Thromboembolism.

Joseph Emmerich, F. R. Rosendaal, Marco Cattaneo et al. · PubMed · 2001 · 326 citations

Medicine, Genetics, Hematology +17