Concepedia

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma

Sergey I. Nikolaev, Donata Rimoldi, Christian Iseli, Armand Valsesia, Daniel Robyr, Corinne Gehrig, Keith Harshman, Michel Guipponi, Olesya V. Bukach, Vincent Zoete,

Nature Genetics · 2011 · 400 citations · 38 references

Concepts

MedicineGeneticsOncologyCancer GeneticsGenomicsMolecular OncologyCancer GenomicsMelanocytic LesionsMelanocytic TumorsMolecular Tumor ProfilingNext-generation Sequencing In OncologySomatic Variant InterpretationHereditary MelanomaMelanocytic Tumor GeneticsMelanocytic Tumor Molecular PathologyMelanocytic Tumor SyndromesTumor Exome Sequencing

References

38

UCSF Chimera—A visualization system for exploratory research and analysis

Eric F. Pettersen, Thomas D. Goddard, Conrad C. Huang et al. · Journal of Computational Chemistry · 2004 · 47.8K citations

Computing, Bioinformatics, Visualization +17

Mutations of the BRAF gene in human cancer

Helen Davies, Graham R. Bignell, Charles Cox et al. · Nature · 2002 · 10.7K citations

Medicine, Genetics, Molecular Genetics +12

The Consensus Coding Sequences of Human Breast and Colorectal Cancers

Tobias Sjöblom, Siân Jones, Laura D. Wood et al. · Science · 2006 · 3.2K citations

Medicine, Genetics, Oncology +17

Somatic mutations affect key pathways in lung adenocarcinoma

Li Ding, Gad Getz, David A. Wheeler et al. · Nature · 2008 · 2.7K citations · Full text

Medicine, Genetics, Oncology +16

Mapping short DNA sequencing reads and calling variants using mapping quality scores

Heng Li, Jue Ruan, Richard Durbin · Genome Research · 2008 · 2.7K citations · Full text

Life Sciences, Bioinformatics, Biology +17