Concepedia

Base-promoted dehydrogenative coupling of benzene derivatives with amides or ethers

Ryota Ueno, Eiji Shirakawa

Organic & Biomolecular Chemistry · 2014 · 25 citations · 35 references

DOI

Concepts

Abstract

Benzene derivatives are introduced into the dehydrogenative coupling via homolytic aromatic substitution (HAS) as arenes that couple with amides/ethers. NaOt-Bu is used as a critical promoter of HAS in combination with t-BuOOt-Bu as an oxidant.

References

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