Concepedia

Base-mediated Coupling

Base-Mediated Coupling is a cross-coupling reaction mechanism in which a base facilitates the formation of a carbon–carbon or carbon–heteroatom bond by promoting transmetalation or oxidative addition through deprotonation or activation of a substrate, distinguishing it from coupling processes reliant solely on transition metal catalysis without base involvement.

135

Publications

6.4K

Citations

473

Authors

173

Institutions

Publications per year

2017–2026

40

Parents

Publications

135

Computational Characterization of the Role of the Base in the Suzuki−Miyaura Cross-Coupling Reaction

Ataualpa Albert Carmo Braga, Nelson H. Morgon, Gregori Ujaque et al. · Journal of the American Chemical Society · 2005 · 343 citations

, , +16

Template-Directed Synthesis, Excited-State Photodynamics, and Electronic Communication in a Hexameric Wheel of Porphyrins

Junzhong Li, Arounaguiry Ambroise, Sung Ik Yang et al. · Journal of the American Chemical Society · 1999 · 230 citations

, , +11

Cross Dehydrogenative Coupling via Base-Promoted Homolytic Aromatic Substitution (BHAS): Synthesis of Fluorenones and Xanthones

Sebastian Wertz, Dirk Leifert, Armido Studer · Organic Letters · 2013 · 191 citations

, , +8

Elucidating Reactivity Differences in Palladium-Catalyzed Coupling Processes:  The Chemistry of Palladium Hydrides

Ivory D. Hills, Gregory C. Fu · Journal of the American Chemical Society · 2004 · 172 citations

, , +13

Breaking the Base Barrier: An Electron-Deficient Palladium Catalyst Enables the Use of a Common Soluble Base in C–N Coupling

Joseph M. Dennis, Nicholas A. White, Richard Y. Liu et al. · Journal of the American Chemical Society · 2018 · 170 citations · Full text

, , +9

1–5 of 135

Authors

473

  1. IN
    Irishi N. N. Namboothiri

    Indian Institute of Technology Bombay, India

    3 publications · 309 citations

    3

    h-index

  2. DY
    Ding‐Yah Yang

    Tunghai University, Taiwan

    3 publications · 162 citations

    3

    h-index

  3. KF
    K.‐O. Feldmann

    University of Münster, Germany

    2 publications · 42 citations

    2

    h-index

  4. NA
    Nicholas A. White

    Colorado State University, United States

    2 publications · 256 citations

    2

    h-index

  5. DF
    David F. Bocian

    University of California, Riverside, United States

    2 publications · 283 citations

    2

    h-index

1–5 of 473

Institutions

173

  1. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    14 publications

    434 citations

  2. Lanzhou University

    Lanzhou, China

    3 h-index

    9 publications

    481 citations

  3. Tohoku University

    Sendai, Japan

    3 h-index

    7 publications

    381 citations

  4. University of Warwick

    Coventry, United Kingdom

    3 h-index

    5 publications

    110 citations

  5. Tunghai University

    Taichung, Taiwan

    3 h-index

    8 publications

    443 citations

  6. University of Delhi

    New Delhi, India

    3 h-index

    12 publications

    323 citations

  7. Shanghai Institute of Organic Chemistry

    Shanghai, China

    3 h-index

    5 publications

    263 citations

  8. Indian Institute of Technology Bombay

    Mumbai, India

    3 h-index

    7 publications

    754 citations

1–8 of 173

Venues

  1. Organic Letters

    OL · 24 publications · 1.5K citations

    21

    h-index

  2. The Journal of Organic Chemistry

    JOC · 19 publications · 740 citations

    15

    h-index

  3. Tetrahedron Letters

    17 publications · 543 citations

    13

    h-index

  4. Journal of the American Chemical Society

    JACS · 10 publications · 1.3K citations

    10

    h-index

  5. Organic & Biomolecular Chemistry

    9 publications · 346 citations

    9

    h-index

1–5