Functional potencies of dopamine agonists and antagonists at human dopamine D2 and D3 receptors

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Pharmacologic Analysis of Drug Receptor Interaction

Kenakin. T. Kenakin · Therapeutic Drug Monitoring · 1988 · 930 citations

Medicine, Pharmacokinetics, Pharmacology +17

Distinct functions of the two isoforms of dopamine D2 receptors

Alessandro Usiello, Ja‐Hyun Baik, Françoise Rougé‐Pont et al. · Nature · 2000 · 725 citations

Medicine, Neuroscience, Pharmacology +14

Pramipexole for the treatment of depressive symptoms in patients with Parkinson's disease: a randomised, double-blind, placebo-controlled trial

Paolo Barone, Werner Poewe, Stefan Albrecht et al. · The Lancet Neurology · 2010 · 560 citations

Medicine, Pharmacology, Pharmacotherapy +14

Dopamine Auto- and Postsynaptic Receptors: Electrophysiological Evidence for Differential Sensitivity to Dopamine Agonists

L.R. Skirboll, Anthony A. Grace, B.S. Bunney · Science · 1979 · 502 citations

Life Sciences, Neuroscience, Pharmacology +17