The α1β1 and α2β1 Integrins Provide Critical Support for Vascular Endothelial Growth Factor Signaling, Endothelial Cell Migration, and Tumor Angiogenesis

Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid

Donald R. Senger, Stephen J. Galli, Ann M. Dvořàk et al. · Science · 1983 · 4K citations

Medicine, Biochemistry, Oncology +13

The MAPK signaling cascade

Rony Seger, Edwin G. Krebs · The FASEB Journal · 1995 · 3.4K citations

Life Sciences, Cell Biology, Molecular Biology +17

Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.

Harold F. Dvorak, Lawrence F. Brown, Michael Detmar et al. · PubMed · 1995 · 3.1K citations

Veterinary Medicine, Physiology, Tumor Microenvironment +9

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

Peter C. Brooks, Anthony M.P. Montgomery, Mauricio Rosenfeld et al. · Cell · 1994 · 2.3K citations

Medicine, Cancer Biology, Oncology +16

Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

Napoleone Ferrara, William J. Henzel · Biochemical and Biophysical Research Communications · 1989 · 2.3K citations

Life Sciences, Cell Biology, Endocrinology +14