Concepedia

Integrin Alpha2beta1

Integrin Alpha2Beta1 is a transmembrane heterodimeric receptor protein that mediates platelet adhesion by specifically recognizing and binding to collagen in the extracellular matrix, thereby initiating platelet activation and thrombus formation under conditions of vascular injury.

725

Publications

48.3K

Citations

3.6K

Authors

926

Institutions

Publications per year

2017–2026

59

Variants

α2β1 Integrin

Parents

Publications

725

Structural Basis of Collagen Recognition by Integrin α2β1

Jonas Emsley, Christopher G. Knight, Richard W. Farndale et al. · Cell · 2000 · 994 citations · Full text

, , +16

The Collagen-binding A-domains of Integrins α1β1 and α2β1Recognize the Same Specific Amino Acid Sequence, GFOGER, in Native (Triple-helical) Collagens

Christopher G. Knight, Laurence F. Morton, Anthony R. Peachey et al. · Journal of Biological Chemistry · 2000 · 682 citations · Full text

, , +17

Glycoprotein VI but not α2β1 integrin is essential for platelet interaction with collagen

Bernhard Nieswandt · The EMBO Journal · 2001 · 542 citations · Full text

, , +16

Smooth Muscle Progenitor Cells in Human Blood

David Simper, Paul G. Stalboerger, Carmelo Panetta et al. · Circulation · 2002 · 498 citations · Full text

, , +11

Peripheralization of hemopoietic progenitors in primates treated with anti-VLA4 integrin.

T Papayannopoulou, B Nakamoto · Proceedings of the National Academy of Sciences · 1993 · 442 citations

, , +16

1–5 of 725

Authors

3.6K

  1. JH
    Jyrki Heino

    University of Turku, Finland

    20 publications · 1.8K citations

    20

    h-index

  2. RW
    Richard W. Farndale

    University of Cambridge, United Kingdom

    21 publications · 3.2K citations

    20

    h-index

  3. MM
    Mary M. Zutter

    Washington University in St. Louis, United States

    15 publications · 1.8K citations

    15

    h-index

  4. SA
    Samuel A. Santoro

    Washington University in St. Louis, United States

    14 publications · 1.8K citations

    14

    h-index

  5. MJ
    Michael J. Barnes

    University of Cambridge, United Kingdom

    13 publications · 2.7K citations

    13

    h-index

1–5 of 3.6K

Institutions

926

  1. University of Turku

    Turku, Finland

    20 h-index

    90 publications

    7.6K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    20 h-index

    97 publications

    15.6K citations

  3. Washington University in St. Louis

    St Louis, United States

    18 h-index

    56 publications

    8.2K citations

  4. Inserm

    Paris, France

    16 h-index

    82 publications

    3.9K citations

  5. University of Cologne

    Cologne, Germany

    14 h-index

    39 publications

    2.6K citations

  6. Harvard University

    Cambridge, United States

    14 h-index

    48 publications

    3.8K citations

  7. Scripps Research Institute

    San Diego, United States

    14 h-index

    29 publications

    2.1K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    13 h-index

    40 publications

    2.2K citations

1–8 of 926

Venues

  1. Journal of Biological Chemistry

    JBC · 58 publications · 6.8K citations

    42

    h-index

  2. Blood

    46 publications · 4.5K citations

    37

    h-index

  3. PubMed

    Repository · 36 publications · 2K citations

    26

    h-index

  4. Biochemical and Biophysical Research Communications

    BBRC · 16 publications · 738 citations

    15

    h-index

  5. Experimental Cell Research

    ECR · 15 publications · 1K citations

    14

    h-index

1–5