Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues

Frank Tietze · Analytical Biochemistry · 1969 · 6K citations

Biochemistry, Nanogram Amounts, Medicine +11

TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis

Karim Bensaad, Atsushi Tsuruta, Mary Selak et al. · Cell · 2006 · 1.9K citations · Full text

Apoptosis, Cell Death, P53-inducible Regulator +3

Neurotoxicity induces cleavage of p35 to p25 by calpain

Ming‐Sum Lee, Young T. Kwon, Mingwei Li et al. · Nature · 2000 · 1.1K citations

Biochemistry, Medicine, Neuropharmacology +4

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1

Ángel Herrero-Méndez, Ángeles Almeida, Emilio Fernández et al. · Nature Cell Biology · 2009 · 828 citations

Metabolic Pathways, Biochemistry, Catabolism +9

Synthesis of the Antioxidant Glutathione in Neurons: Supply by Astrocytes of CysGly as Precursor for Neuronal Glutathione

Ralf Dringen, Brigitte Pfeiffer, Bernd Hamprecht · Journal of Neuroscience · 1999 · 586 citations · Full text

Hr Incubation, Lipid Peroxidation, Glucocorticoid +18