Tissue-specific analysis of chromatin state identifies temporal signatures of enhancer activity during embryonic development

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Ben Langmead, Cole Trapnell, Mihai Pop et al. · Genome biology · 2009 · 23K citations · Full text

Life Sciences, Bioinformatics, High-performance Computing +15

Model-based Analysis of ChIP-Seq (MACS)

Yong Zhang, Tao Liu, Clifford A. Meyer et al. · Genome biology · 2008 · 19.9K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +11

Bioconductor: open software development for computational biology and bioinformatics

Robert Gentleman, Vincent J. Carey, Douglas M. Bates et al. · Genome biology · 2004 · 12.5K citations · Full text

Life Sciences, Bioinformatics, Computational Biology +8

High-Resolution Profiling of Histone Methylations in the Human Genome

Artem Barski, Suresh Cuddapah, Kairong Cui et al. · Cell · 2007 · 6.9K citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Histone H3K27ac separates active from poised enhancers and predicts developmental state

Menno P. Creyghton, Albert W. Cheng, G. Grant Welstead et al. · Proceedings of the National Academy of Sciences · 2010 · 4.5K citations · Full text

Life Sciences, Developmental Biology, Genetics +17