Concepedia

Tissue-specific Enhancer Activity

Tissue-Specific Enhancer Activity is a genomic regulatory phenomenon in which enhancer elements drive gene expression in a restricted spatial pattern confined to particular cell types or tissues, distinguished by their dependence on lineage-specific transcription factors and chromatin accessibility landscapes.

410

Publications

33.7K

Citations

2.2K

Authors

591

Institutions

Publications per year

2017–2026

64

Parents

Publications

410

An atlas of active enhancers across human cell types and tissues

Robin Andersson, Claudia Gebhard, Irene Miguel-Escalada et al. · Nature · 2014 · 2.8K citations · Full text

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SOX9 Is a Potent Activator of the Chondrocyte-Specific Enhancer of the Proα1(II) Collagen Gene

Véronique Lefebvre, Wendong Huang, Vincent R. Harley et al. · Molecular and Cellular Biology · 1997 · 1.1K citations · Full text

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B Lineage—Specific Interactions of an Immunoglobulin Enhancer with Cellular Factors in Vivo

Anne Ephrussi, George M. Church, Susumu Tonegawa et al. · Science · 1985 · 860 citations

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MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-β-induced collagen expression via inhibition of E-box repressors

Mitsuo Kato, Jane Zhang, Mei Wang et al. · Proceedings of the National Academy of Sciences · 2007 · 699 citations · Full text

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LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]

Adam Travis, Abraham Amsterdam, Chantal Bélanger et al. · Genes & Development · 1991 · 623 citations · Full text

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1–5 of 410

Authors

2.2K

  1. NA
    Nadav Ahituv

    University of California, San Francisco, United States

    6 publications · 553 citations

    6

    h-index

  2. PL
    Pamela L. Mellon

    University of California San Diego, United States

    6 publications · 893 citations

    6

    h-index

  3. BD
    Benoît De Crombrugghe

    The University of Texas MD Anderson Cancer Center, United States

    6 publications · 1.8K citations

    6

    h-index

  4. AV
    Axel Visel

    Lawrence Berkeley National Laboratory, United States

    4 publications · 396 citations

    5

    h-index

  5. BL
    Beatriz Levy-Wilson

    Gladstone Institutes, United States

    5 publications · 205 citations

    5

    h-index

1–5 of 2.2K

Institutions

591

  1. Harvard University

    Cambridge, United States

    19 h-index

    110 publications

    11.4K citations

  2. University of California, San Francisco

    San Francisco, United States

    16 h-index

    57 publications

    5.6K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    15 h-index

    38 publications

    7.8K citations

  4. National Institutes of Health

    Bethesda, United States

    15 h-index

    61 publications

    3.7K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    11 h-index

    39 publications

    1.9K citations

  6. The University of Texas MD Anderson Cancer Center

    Houston, United States

    10 h-index

    50 publications

    8.6K citations

  7. University of California San Diego

    San Diego, United States

    10 h-index

    36 publications

    4K citations

  8. University of Pennsylvania

    Philadelphia, United States

    10 h-index

    48 publications

    2.6K citations

1–8 of 591

Venues

  1. Molecular and Cellular Biology

    MCB · 67 publications · 5.8K citations

    40

    h-index

  2. Journal of Biological Chemistry

    JBC · 51 publications · 3.1K citations

    33

    h-index

  3. Nucleic Acids Research

    20 publications · 846 citations

    18

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 20 publications · 3.5K citations

    18

    h-index

  5. Development

    17 publications · 1.6K citations

    17

    h-index

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