Concepedia

Constitutive activity of the histamine H1 receptor reveals inverse agonism of histamine H1 receptor antagonists

Remko A. Bakker, Kerstin Wieland, Henk Timmerman, Rob Leurs

European Journal of Pharmacology · 2000 · 167 citations · 6 references

DOI

Concepts

References

6

Inverse agonism: pharmacological curiosity or potential therapeutic strategy?

Graeme Milligan, Richard A. Bond, Melanie Lee · Trends in Pharmacological Sciences · 1995 · 294 citations

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Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors.

Martine J. Smit, Rob Leurs, A. E. Alewijnse et al. · Proceedings of the National Academy of Sciences · 1996 · 245 citations

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Mutational Analysis of the Antagonist-binding Site of the Histamine H1 Receptor

Kerstin Wieland, Antonius ter Laak, Martine J. Smit et al. · Journal of Biological Chemistry · 1999 · 122 citations · Full text

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Increased expression of histamine H<sub>1</sub> receptor mRNA in allergic rhinitis

Noriko Iriyoshi, Kazuhiko Takeuchi, Atsushi Yuta et al. · Clinical & Experimental Allergy · 1996 · 92 citations

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Pharmacological and Functional Characterisation of the Wild—Type and Site—Directed Mutants of the Human H<sub>1</sub>Histamine Receptor Stably Expressed in CHO Cells

Nicole Moguilevsky, Francesca Varsalona, JEAN-PAUL GUILLAUME et al. · Journal of Receptors and Signal Transduction · 1995 · 49 citations · Full text

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