Individual Neuropeptides Regulate Gut‐Associated Lymphoid Tissue Integrity, Intestinal Immunoglobulin A Levels, and Respiratory Antibacterial Immunity

Abstract

Supplementation of IV-TPN with CCK, gastrin, and NT prevents GALT atrophy, primarily in the distal bowel. Intestinal IgA levels improve but not to normal levels. CCK and gastrin reversed IV-TPN-induced effects on antibacterial pneumonia in immunized animals while NT did not.