Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice.

Robert A. Seder, W E Paul, Mark M. Davis et al. · The Journal of Experimental Medicine · 1992 · 1K citations · Full text

Adaptive Immune System, T-regulatory Cell, Immunology +19

The Duration of Antigenic Stimulation Determines the Fate of Naive and Effector T Cells

Giandomenica Iezzi, Klaus Karjalainen, Antonio Lanzavecchia · Immunity · 1998 · 891 citations · Full text

Autoimmune Disease, Adaptive Immune System, T-regulatory Cell +11

Normal Development of Mice Deficient in β ₂ M, MCClass I Proteins, and CD8 ⁺ T Cells

Beverly H. Koller, Philippa Marrack, John W. Kappler et al. · Science · 1990 · 877 citations

IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression.

Linna Ding, Peter S. Linsley, Long Huang et al. · The Journal of Immunology · 1993 · 842 citations

T-regulatory Cell, Immune Regulation, Immunology +17

Interaction between CD4 and class II MHC molecules mediates cell adhesion

Carolyn A. Doyle, Jack L. Strominger · Nature · 1987 · 819 citations

Class Ii Mhc, Cell Adhesion, Immunology +9