Concepedia

Expedient Total Syntheses of WIN 64745 and WIN 64821

Organic Letters · 2008 · 82 citations · 24 references

Abstract

Bispyrrolidinoindoline diketopiperazine alkaloids were synthesized from a common intermediate in seven steps from commercially available amino acids. This versatile synthetic strategy has led to the accomplishment of the first total synthesis of heterodimeric WIN 64745 and a novel approach to homodimeric WIN 64821.

References

24

Chemistry of the Hexahydropyrrolo[2,3-b]indoles: Configuration, Conformation, Reactivity, and Applications in Synthesis

David Crich, Abhisek Banerjee · Accounts of Chemical Research · 2007 · 406 citations

Chemical Engineering, Enantioselective Synthesis, Engineering +11

Iodotrimethylsilane—a versatile synthetic reagent

George A. Olah, Subhash C. Narang · Tetrahedron · 1982 · 300 citations

Organic Chemistry, Derivative (Chemistry), Synthetic Chemistry +1

Concise Total Synthesis of (−)‐Calycanthine, (+)‐Chimonanthine, and (+)‐Folicanthine

Mohammad Movassaghi, Michael A. Schmidt · Angewandte Chemie International Edition · 2007 · 282 citations

Diversity Oriented Synthesis, Natural Product Synthesis, Bioorganic Chemistry +14

Total Synthesis of 5-N-Acetylardeemin and Amauromine: Practical Routes to Potential MDR Reversal Agents

Kristopher M. Depew, Stephen P. Marsden, Danuta Zatorska et al. · Journal of the American Chemical Society · 1999 · 244 citations

Bioorganic Chemistry, Mdr Reversal Agents, Organic Chemistry +17

Direct Stereo- and Enantiocontrolled Synthesis of Vicinal Stereogenic Quaternary Carbon Centers. Total Syntheses of meso- and (−)-Chimonanthine and (+)-Calycanthine

Larry E. Overman, Daniel V. Paone, Brian A. Stearns · Journal of the American Chemical Society · 1999 · 221 citations

Engineering, Direct Stereo-, Heck Reaction +12