Characteristics of binding of [3H]NE-100, a novel sigma-receptor ligand, to guinea-pig brain membranes

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

W R Martin, C. G. Eades, JP Thompson et al. · Journal of Pharmacology and Experimental Therapeutics · 1976 · 3K citations

Medicine, Pharmacology, Veterinary Pharmacology +16

A proposal for the classification of sigma binding sites

Rémi Quirion, Wayne D. Bowen, Yossef Itzhak et al. · Trends in Pharmacological Sciences · 1992 · 754 citations

Pharmacy, Molecular Biology, Molecular Recognition +7

Beta Adrenergic Receptor Binding in Membrane Preparations from Mammalian Brain

David B. Bylund, Solomon H. Snyder · Molecular Pharmacology · 1976 · 574 citations · Full text

Medicine, Neurobiology, Pharmacology +16

Evidence for sigma opioid receptor: binding of [3H]SKF-10047 to etorphine-inaccessible sites in guinea-pig brain.

Tsung‐Ping Su · Journal of Pharmacology and Experimental Therapeutics · 1982 · 434 citations

Medicine, Neurobiology, Pharmacology +17