Nature Cell Biology · 2006 · 470 citations · 42 references
Life SciencesCancer BiologyMolecular BiologyCancer GeneticsDna RepairMolecular OncologyApoptosis In CancerApoptosis RegulationApoptotic SignalingDna Damage SignalingDna Damage-induced ApoptosisN-linked GlycosylationO-glcnacylation In CancerO-linked N-acetylglucosamine ModificationTumor Suppressor P53
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Mdm2 promotes the rapid degradation of p53
Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations
Regulation of p53 stability by Mdm2
Michael H.G. Kubbutat, Stephen N. Jones, Karen H. Vousden · Nature · 1997 · 3.3K citations
<i>p53</i> Status and the Efficacy of Cancer Therapy in Vivo
Scott W. Lowe, Stephan Bodis, Andrea I. McClatchey et al. · Science · 1994 · 1.5K citations
Medicine, Cancer Biology, Oncology +17
mdm2 expression is induced by wild type p53 activity.
Yaacov Barak, T. Juven, Rebecca Haffner et al. · The EMBO Journal · 1993 · 1.3K citations · Full text
DNA Damage-Induced Activation of p53 by the Checkpoint Kinase Chk2
Atsushi Hirao, Young‐Yun Kong, Shuhei Matsuoka et al. · Science · 2000 · 1.3K citations