IL-4 Triggers Autoimmune Diabetes by Increasing Self-Antigen Presentation within the Pancreatic Islets

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

Federica Sallusto, Antonio Lanzavecchia · The Journal of Experimental Medicine · 1994 · 5.2K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Regulatory T Cell Clones Induced by Oral Tolerance: Suppression of Autoimmune Encephalomyelitis

Youhai Chen, Vijay K. Kuchroo, Jun-ichi Inobe et al. · Science · 1994 · 2K citations

Life Sciences, Immunology, Autoimmunity +16

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice.

Robert A. Seder, W E Paul, Mark M. Davis et al. · The Journal of Experimental Medicine · 1992 · 1K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system.

Chyi‐Song Hsieh, Amy B. Heimberger, Jennifer S. Gold et al. · Proceedings of the National Academy of Sciences · 1992 · 753 citations

Life Sciences, Cell Biology, Immunology +17

Maturation, Activation, and Protection of Dendritic Cells Induced by Double-stranded RNA

Marina Cella, Mariolina Salio, Yoichi Sakakibara et al. · The Journal of Experimental Medicine · 1999 · 713 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17