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A magnetically driven oscillating probe microscope for operation in liquids
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1996
Year
Probe MicroscopeEngineeringMicroscopyMagnetic ResonanceMolecular BiologyBiomedical EngineeringAcoustic ExcitationMagnetismMicroscopy MethodExcitation AmplitudesLight MicroscopyMicrofluidicsDna Plasmid BoundBiophysicsPhysicsMagnetic MeasurementMicrofabricationScanning Probe MicroscopyApplied PhysicsScanning Force MicroscopyMedicineAcoustic Microscopy
Oscillating probe atomic force microscopy in fluids is simplified when an oscillating force is applied directly to a magnetized cantilever using a solenoid. The response of the detector is simpler than that obtained with acoustic excitation. Reliable operation over a broad frequency range is achieved with excitation amplitudes of a few nm. This lower amplitude appears to facilitate imaging by means of small asperities on the tip. Images of a DNA plasmid bound weakly to mica in water have a full width of 5 nm when scanned with tips of a nominal macroscopic radius of curvature of 50 nm.