<scp>KH902</scp> suppresses high glucose‐induced migration and sprouting of human retinal endothelial cells by blocking <scp>VEGF</scp> and <scp>PIGF</scp>

Abstract

Our study indicates that KH902 suppresses high glucose-induced migration and sprouting of HRECs through not only binding VEGF, but also PlGF to inhibit the activation of Src-Akt1-Erk1/2 pathway. KH902 is a drug that potentially inhibits angiogenic pathways involving in DR or other ocular neovascular diseases.