Cell · 2009 · 280 citations · 41 references
MedicineCancer BiologyMolecular BiologyCarcinogenesisNeoplasiaTumor ProgressionCancer InitiationCancer ProgressionColonic DiseasesColonic DisordersColorectal CancerGastrointestinal NeoplasmsApc InactivationColon AdenomaColon Tumor PromotionColonic AdenocarcinomaColorectal AdenomasColorectal Carcinogenesis PathophysiologyFamilial Adenomatous Polyposis
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Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC
Patrice J. Morin, Andrew B. Sparks, Vladimír Kořínek et al. · Science · 1997 · 3.9K citations
β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
Osamu Tetsu, Frank McCormick · Nature · 1999 · 3.6K citations
Medicine, Cell Biology, Oncology +14
Prevalence of ras gene mutations in human colorectal cancers
Johannes L. Bos, Eric R. Fearon, Stanley R. Hamilton et al. · Nature · 1987 · 1.9K citations
Detection of high incidence of K-ras oncogenes during human colon tumorigenesis
Kathleen Forrester, Concepción Almoguera, Kyuhyung Han et al. · Nature · 1987 · 1.1K citations
Medicine, Cancer Biology, Oncology +12
Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.
Andrew B. Sparks, Patrice J. Morin, Bert Vogelstein et al. · PubMed · 1998 · 1K citations